Network-Based Coverage of Mutational Profiles Reveals Cancer Genes
نویسندگان
چکیده
منابع مشابه
Network-based coverage of mutational profiles reveals cancer genes
A central goal in cancer genomics is to identify the somatic alterations that underpin tumor initiation and progression. While commonly mutated cancer genes are readily identifiable, those that are rarely mutated across samples are difficult to distinguish from the large numbers of other infrequently mutated genes. We introduce a method, nCOP, that considers per-individual mutational profiles w...
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ژورنال
عنوان ژورنال: Cell Systems
سال: 2017
ISSN: 2405-4712
DOI: 10.1016/j.cels.2017.09.003